If you go bankrupt the property depends on the equity. Low or negative equity then may keep the house, same with buying out the equity for the bankruptcy.
You cannot normally be a company director while bankrupt but some people do run a self employed business.
You really should speak to an IP before making such a serious decision to see if BKY is the best option for you.
If you have equity in your property it is at risk of being repossessed and sold or a third party having to find funds to buy out the Trustee's interest.
There are other ramifications too:
You may not be able to continue trading
Assets are at risk
Some debt survives bky
credit rating damaged 6 years
Windfalls will vest in estate whilst bkpt
you may have to pay income contributions for 3 years
you cannot be a Director
Also consider an IVA, Debt Relief Order and Debt Management Plan.