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Apple iPad web site says: Works well with others: Numbers on iPad lets you open spreadsheets created using iWork or Microsoft Office. So if someone emails you a Numbers or Excel file, you can easily import it into Numbers for iPad. To share your work, export your spreadsheet as a Numbers file for Mac or PDF document, then email it to anyone. You can also upload it to iWork.com public beta so anyone on a Mac or PC can view your spreadsheet.
I would suggest you look at Documents to Go or Quick Office as these applications have a long pedigree of MS Office to handheld synchronisation with native documents and spreadsheets.